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Journal of Virology | 23.12.15

Robin Fears, Vollker ter Meulen. (2016) European Academies Advise on Gain-of-Function Studies in Influenza Virus Research. Journal of Virology, March 2016, Volume 90, Number 5, 2162-2164

Abstract: Gain-of-function (GoF) studies to understand factors affecting transmissibility of potentially pandemic pathogens are controversial. The European Academies Science Advisory Council (EASAC) recently published consensus recommendations relating to GoF research review and management on self-regulation and harmonization; bioethical considerations; benefit-risk assessment; biosafety, and biosecurity advisory options; and publication of sensitive information. A layered approach to integration of responsibilities must include conforming to the stringent rules and guidance already existing. Further commitment is essential to extend the debate on issues worldwide.

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